| 摘要 |
A tablet containing a phosphate-binding polymer, which has an average particle size of 400 mum or less, contains particles of 500 mum or less in particle size at a ratio of 90% or more and has a moisture content of 1 to 14%, together with crystalline cellulose and/or low substituted hydroxypropylcellulose, and a process for producing the same are disclosed. The phosphate-binding polymer tablet according to the present invention contains the active component at a high ratio, is excellent in the ability to bind to phosphate and is a quickly disintegrated in an acidic to a neutral region while being little affected by the stirring strength. Accordingly, it is an excellent preparation capable of regulating changes in bioavailability due to the gastrointestinal motions and pH value.
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