发明名称 |
Vertebrate embryonic pattern-inducing proteins |
摘要 |
The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
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申请公布号 |
US6384192(B1) |
申请公布日期 |
2002.05.07 |
申请号 |
US19970957874 |
申请日期 |
1997.10.20 |
申请人 |
PRESIDENT & FELLOWS OF HARVARD COLLEGE;IMPERIAL CANCER RESEARCH TECHNOLOGY, LTD. |
发明人 |
INGHAM PHILIP W.;MCMAHON ANDREW P.;TABIN CLIFFORD J. |
分类号 |
A01K67/027;A01K67/033;A61K38/00;C07K14/46;C07K14/475;C12N5/08;C12N15/12;C12N15/18;C12N15/85;(IPC1-7):C07K14/475 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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