| 发明名称 |
Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitor activity. |
| 摘要 |
4-(4-(-Chlorophenyl)piperazin-1-yl)sulfonylmethyl)-tetrahydor yran-4-carboxylic acid and the corresponding N-hydroxy amide, and derivatives thereof, are useful as therapeutic agents. |
| 申请公布号 |
ZA200103671(B) |
申请公布日期 |
2002.05.07 |
| 申请号 |
ZA20010003671 |
申请日期 |
2001.05.07 |
| 申请人 |
DARWIN DISCOVERY LIMITED |
发明人 |
ANDREW DOUGLAS BAXTER;DAVID ALAN OWEN;ROBERT JOHN WATSON |
| 分类号 |
A61K31/496;A61P1/00;A61P1/02;A61P1/04;A61P7/02;A61P7/04;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P15/00;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P25/06;A61P25/28;A61P27/02;A61P29/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;A61P37/06;A61P37/08;A61P39/02;A61P43/00;C07D309/08 |
主分类号 |
A61K31/496 |
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