| 发明名称 |
Net, a transcription factor of the tcf family, as regulator of angiogenic factorexpression |
| 摘要 |
The present invention relates to the regulation of the activity of NET (ERP/SAP-2) protein and to compounds which modify or regulate NET protein activity. The invention further relates to methods of screening for agonists or antagonists of NET in order to identify new pro-angiogenic or anti-angiogenic compounds and to therapeutic uses of these compounds. The invention also relates to transgenic animals bearing mutations in NET gene. <IMAGE> |
| 申请公布号 |
AU1908602(A) |
申请公布日期 |
2002.05.06 |
| 申请号 |
AU20020019086 |
申请日期 |
2001.10.23 |
| 申请人 |
AVENTIS PHARMA S.A.;INSERM |
发明人 |
BOHDAN WASYLYK;MARIE-CHRISTINE MULTON;ABDELKADER AYADI;HONG ZHENG |
| 分类号 |
A01K67/027;A61K31/275;A61K31/352;A61K31/4439;A61K31/7088;A61K38/00;A61K38/17;A61K39/395;A61K45/00;A61K48/00;A61P1/04;A61P1/16;A61P3/04;A61P5/14;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P11/02;A61P11/06;A61P13/12;A61P15/00;A61P17/00;A61P19/00;A61P19/02;A61P21/00;A61P25/28;A61P27/02;A61P29/00;A61P31/00;A61P35/00;A61P37/06;A61P37/08;C12N15/09;C12N15/85;C12Q1/02;C12Q1/48;G01N33/15;G01N33/50;G01N33/566;G01N33/574;G01N33/68 |
主分类号 |
A01K67/027 |
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