AGENTS FOR RECOVERYING FROM OR PREVENTING FATIGUE IN THE CENTRAL NERVE SYSTEM AND FOODS FOR RECOVERYING FROM OR PREVENTING FATIGUE

摘要

Agents for preventing fatigue in the central nerve system (cerebral fatigue) or recovering from cerebral fatigue which contain branched amino acids including L-valine, L-leucine and L-isoleucine and/or a 2-aminobicyclo[2.2.1]heptane-2-carboxylic acid. These agents are obtained by a method of screening central nerve system fatigue inhibitors which comprises measuring the degree of fatigue inhibition by the treadmill running method with the use of albumin-free rats or tryptophan-deficient rat. These agents can be provided not only in the form of injections or transfusions but also as foods for recovering from fatigue in the central nerve system or preventing fatigue, for example, solid preparations appropriate for the administration such as tablets, granules or dusts obtained by blending with starch, lactose and the like and various beverages (i.e., so-called health drinks).