发明名称 VACCINE IMMUNOTHERAPY FOR IMMUNE SUPPRESSED PATIENTS
摘要 A method for overcoming mild to moderate immune suppression includes the ste ps of inducing production of naïve T-cells and restoring T-cell immunity. A method of vaccine immunotherapy includes the steps of inducing production of naïve T-cells and exposing the naïve T-cells to endogenous or exogenous antigens at an appropriate site. Additionally, a method for unblocking immunization at a regional lymph node includes the steps of promoting differentiation and maturation of immature dendritic cells at a regional lym ph node and allowing presentation of processed peptides by resulting mature dendritic cells, thus, for example, exposing tumor peptides to T-cells to ga in immunization of the T-cells. Further, a method of treating cancer and other persistent lesions includes the steps of administering an effective amount o f a natural cytokine mixture as an adjuvant to endogenous or exogenous administered antigen to the cancer or other persistent lesions.
申请公布号 CA2464228(A1) 申请公布日期 2002.05.02
申请号 CA20012464228 申请日期 2001.10.26
申请人 IMMUNO-RX, INC. 发明人 HADDEN, JOHN W.
分类号 A61K45/00;A61K31/192;A61K31/365;A61K31/405;A61K31/415;A61K31/664;A61K38/00;A61K38/19;A61K39/00;A61K39/39;A61P31/00;A61P35/00;C12N15/19;C12P21/08 主分类号 A61K45/00
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