NOVEL <i>S. PYOGENES</i> DNA POLYMERASE III HOLOENZYME NUCLEIC ACID MOLECULES AND PROTEINS

摘要

S. pyogenes nucleic acid molecules encoding polC, dnaE, holA, holB, dnaX, dnaN, SSB, dnaG, dnaQ, dnaA and dnaB proteins, as well as nucleic acid molecules comprising oriC are provided. The encoded proteins are also provided. The nucleic acid molecules and proteins are useful for reconstituting replicases and polymerases for sequencing, amplification, and screening for compounds which modulate the function of the polymersase or replicase.