Verwendung CD28 spezifischer monoklonaler Antikörper zur Stimulation von Blutzellen, welche kein CD28 tragen

摘要

The invention relates to the use of monoclonal antibodies that are specific of CD28 and that activate the T lymphocytes of several to all subtypes without occupying an antigen receptor of the T lymphocytes, thereby activating the T lymphocytes in an antigen-unspecific manner. The invention also relates to an analog thereof for producing a pharmaceutical preparation for stimulating blood cells that lack CD28, or for treating diseases that are characterized by a reduced number of such blood cells.