| 摘要 |
Gene Delivery Vectors and Their Uses Preparations of infectious viral particles include viral particles which can act as helper virus for adeno-associated virus (AAV), and include particles comprising DNA (i) that includes at least one chosen nucleic acid sequence for delivery to target host cells, and further encoding proteins and replicating functions which together are sufficient, when said particles of said preparation infect first target host cell, for assembly and release, from said first target cells of infectious recombinant AAV particles that comprise said chosen nucleic acid sequence, whereby said infectious recombinant AAV particles are able in turn to infect second target host cells, and cause expression of said DNA (i) in said infected second target host cells.
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