发明名称 |
METHOD FOR GENERATING A LIBRARY OF OLIGONUCLEOTIDES COMPRISING A CONTROLLED DISTRIBUTION OF MUTATIONS |
摘要 |
Methods are disclosed for producing libraries of nucleic acid molecules whic h libraries are derived from a nucleic acid template. The libraries comprise variant nucleic acids which are produced from a mutagenesis strategy using, e.g., a plurality of defined mutagenic and/or non-mutagenic primers and specific reaction conditions which favor the production of varied combinatorial mutants.
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申请公布号 |
CA2426774(A1) |
申请公布日期 |
2002.05.02 |
申请号 |
CA20012426774 |
申请日期 |
2001.10.12 |
申请人 |
GENENCOR INTERNATIONAL, INC. |
发明人 |
SCHELLENBERGER, VOLKER;CALDWELL, ROBERT M. |
分类号 |
C07B61/00;C12N15/10;(IPC1-7):C12N15/10;C12N9/56;C12Q1/68 |
主分类号 |
C07B61/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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