The present invention relates to newly identified CTPase activator proteins (GAPs). The invention also relates to polynucleotides encoding the proteins. The invention further relates to methods using the polypeptides and polynucleotides as a target for diagnosis and treatment in GAP-mediated or related disorders. The invention further relates to drug-screening methods using the polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the polypeptides and polynucleotides. The invention further relates to procedures for producing the polypeptides and polynucleotides.
申请公布号
WO0164873(A3)
申请公布日期
2002.05.02
申请号
WO2001US06194
申请日期
2001.02.27
申请人
MILLENNIUM PHARMACEUTICALS, INC.;GLUCKSMANN, MARIA, ALEXANDRA;MEYERS, RACHEL, A.