| 发明名称 |
MODULATION OF OLIGONUCLEOTIDE CpG-MEDIATED IMMUNE STIMULATION BY POSITIONAL MODIFICATION OF NUCLEOSIDES |
| 摘要 |
The invention provides methods for modulating the immune response caused by CpG-containing oligonucleotides. The methods according to the invention enable decreasing the immunostimulatory effect for antisense applications. |
| 申请公布号 |
EP1200580(A2) |
申请公布日期 |
2002.05.02 |
| 申请号 |
EP20000955527 |
申请日期 |
2000.08.14 |
| 申请人 |
HYBRIDON, INC. |
发明人 |
AGRAWAL, SUDHIR |
| 分类号 |
C12N15/09;A61K31/712;A61K31/7125;A61K48/00;A61P31/18;A61P37/04;A61P37/06;C07H21/00;C07H21/04;C12N15/117;(IPC1-7):C12N15/11 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
