| 发明名称 |
MAMMALIAN METABOLITES OF A TACHYKININ RECEPTOR ANTAGONIST |
| 摘要 |
This invention is concerned with mammalian metabolites of the compound 2-(R) - (1-(R)-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(S)-(4-fluoro)-phenyl-4-(3- (5- oxo-1H,4H-1,2,4-triazolo)methylmorpholine which is a tachykinin receptor antagonist that is useful in the prevention and treatment of certain disorders, including emesis and psychiatric disorders such as depression and anxiety.
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| 申请公布号 |
CA2425908(A1) |
申请公布日期 |
2002.05.02 |
| 申请号 |
CA20012425908 |
申请日期 |
2001.10.23 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
CHIU, SHUET-HING LEE;HUSKEY, SU-ER WU |
| 分类号 |
C07D413/06;A61K31/09;A61K31/121;A61K31/165;A61K31/192;A61K31/5375;A61K31/5377;A61P1/08;A61P25/22;A61P25/24;C07C43/315;C07C45/28;C07C45/64;C07C45/71;C07C49/255;C07C49/84;C07C59/88;C07C59/90;C07D265/32;C07D265/33;C07D405/06;(IPC1-7):A61K31/535 |
主分类号 |
C07D413/06 |
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