发明名称 |
Protein tyrosine phosphatase 1B (PTP-1B) inhibitors containing two ortho-substituted aromatic phosphonates |
摘要 |
The invention encompasses the novel class of compounds represented by formula I, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes, obesity, and diabetes-related diseases.
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申请公布号 |
US2002052347(A1) |
申请公布日期 |
2002.05.02 |
申请号 |
US20000745220 |
申请日期 |
2000.12.21 |
申请人 |
LEBLANC YVES;DUFRESNE CLAUDE;GAUTHIER JACQUES YVES;YOUNG ROBERT |
发明人 |
LEBLANC YVES;DUFRESNE CLAUDE;GAUTHIER JACQUES YVES;YOUNG ROBERT |
分类号 |
A61K45/00;A61K31/663;A61P1/04;A61P1/18;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P25/00;A61P35/00;A61P43/00;C07F9/38;C07F9/40;(IPC1-7):C07F9/38;A61K31/662 |
主分类号 |
A61K45/00 |
代理机构 |
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地址 |
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