This invention provides particles of a therapeutic protein core coated with a surfactant that are suitable for pulmonary delivery to the deep lung of a patient in need thereof. Spray drying processes for preparing powders of the core protein particles and powders of the respirable, surfactant-coated, therapeutic protein particles are provided.
申请公布号
WO0193837(A3)
申请公布日期
2002.05.02
申请号
WO2001US16472
申请日期
2001.05.31
申请人
ELI LILLY AND COMPANY;BHAT, MEENAKSHI, GANAPATI;CUFF, GEORGE, WILLIAM;WOLFF, RONALD, KEITH
发明人
BHAT, MEENAKSHI, GANAPATI;CUFF, GEORGE, WILLIAM;WOLFF, RONALD, KEITH