| 摘要 |
The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The invention delivers therapeutic viral vectors via rAAV affixed to support matrixes (i.e., sutures, surgically implantable materials, grafts, and the like). |
| 申请人 |
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL;MONAHAN, PAUL, E.;SAMULSKI, RICHARD, J.;RABINOWITZ, JOSEPH, E. |
发明人 |
MONAHAN, PAUL, E.;SAMULSKI, RICHARD, J.;RABINOWITZ, JOSEPH, E. |
