A method of characterizing the biological activity of a candidate compound may include exposing cells to the candidate compound, and then exposing the cells to a repetitive application of electric fields so as to set the transmembrane potential to a level corresponding to a pre-selected voltage dependent state of a target ion channel.
申请公布号
WO0208748(A3)
申请公布日期
2002.05.02
申请号
WO2001US21652
申请日期
2001.07.09
申请人
AURORA BIOSCIENCES CORPORATION;MAHER, MICHAEL, P.;GONZALEZ, JESUS, E., III