| 发明名称 |
Pro-protein converting enzyme |
| 摘要 |
The present invention relates to the cloning of human pro-protein converting enzyme 5 (PC5) CDNA isolated from human adrenal gland messenger RNA. Additionally, this invention relates to a method for reducing restenosis occurring at an injured vascular site comprising delivering to the injured site an antisense nucleic acid to suppress the expression of human PC5.
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| 申请公布号 |
US6380171(B1) |
申请公布日期 |
2002.04.30 |
| 申请号 |
US19990214555 |
申请日期 |
1999.09.13 |
| 申请人 |
CLINICAL RESEARCH INSTITUTE OF MONTREAL;UNIVERSITE DE MONTREAL;CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL |
发明人 |
DAY ROBERT;SEIDAH NABIL G.;MARTEL RéMI;CHRéTIEN MICHEL;REUDELHUBER TIM;LECLERC GUY |
| 分类号 |
A61K31/70;A61K38/00;C07H21/04;C12N9/64;C12N15/57;C12N15/85;C12P21/06;(IPC1-7):A61K31/70;A01N43/04;C12Q1/68 |
主分类号 |
A61K31/70 |
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