发明名称 |
Carboxamidothiazole derivatives, preparation, pharmaceutical compositions containing them |
摘要 |
The present invention relates to cholecystokinin (CCK)-agonist substituted thiazoles of formula:in which R1 is a substituted phenyl group, R2 is a group chosen from CH2-R7, (CH2)2-R7, S-CH2-R7, CH2-S-R7 and (C5-C8)alkyl with R7 being a (C5-C7)cycloalkyl group, and R3 is a groupwith R8 being a group (CH2)nR15 orand R15 being COOH or COO(C1-C4)alkyl. The invention also relates to a process for the preparation of the pharmaceutical compositions containing them and to their uses for the preparation of medicines.
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申请公布号 |
US6380230(B1) |
申请公布日期 |
2002.04.30 |
申请号 |
US20000508830 |
申请日期 |
2000.06.02 |
申请人 |
SANOFI-SYNTHELABO |
发明人 |
BRODIN ROGER;BOIGEGRAIN ROBERT;BIGNON ERIC;MOLIMARD JEAN CHARLES;OLLIERO DOMINIQUE |
分类号 |
C07D417/12;A61K31/405;A61K31/425;A61K31/427;A61K31/44;A61P1/00;A61P1/06;A61P3/04;A61P25/00;A61P43/00;C07D;C07D209/42;C07D277/46;C07D417/00;C07D417/02;C07D417/04;C07D417/14;C07D471/04;(IPC1-7):C07D417/12 |
主分类号 |
C07D417/12 |
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