| 发明名称 |
Novel neurokinin antagonists, method for the production thereof and pharmaceutical compositions containing said compounds |
| 摘要 |
The invention relates to novel compounds of formula (I) or the pharmaceutically acceptable salts thereof, wherein R<1> represents 3-hydroxypropyl, 1,3-dihydroxyprop-2-yl or C3-C6 cycloalkylmethyl, and R<2>, R<3>, R<4> and Ar have the designations cited in the description. The invention also relates to the production and use of said compounds. The inventive novel compounds are valuable neurokinin (tachykinin) antagonists. |
| 申请公布号 |
AU2361702(A) |
申请公布日期 |
2002.04.29 |
| 申请号 |
AU20020023617 |
申请日期 |
2001.10.16 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMA KG |
发明人 |
HORST DOLLINGER;FRANZ ESSER;BIRGIT JUNG;KURT SCHROMM;GEORG SPECK |
| 分类号 |
A61K31/4468;A61K31/4525;A61P1/04;A61P1/08;A61P9/02;A61P9/12;A61P9/14;A61P11/00;A61P11/06;A61P11/08;A61P11/10;A61P13/02;A61P13/10;A61P15/08;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P19/02;A61P19/08;A61P19/10;A61P25/06;A61P25/08;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P27/02;A61P27/16;A61P29/00;A61P31/22;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D211/58;C07D405/06 |
主分类号 |
A61K31/4468 |
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