An immune response against an influenza virus is elicited in a subject by administering a vaccine composition comprising a nucleic acid sequence that encodes an influenza virus M2 antigen. The nucleic acid sequence is not present in a recombinant viral vector. The nucleic acid sequence is expressed in the subject to provide the influenza virus M2 antigen in an amount sufficient to elicit an immune response.
申请公布号
WO0183528(A3)
申请公布日期
2002.04.25
申请号
WO2001GB01924
申请日期
2001.05.01
申请人
POWDERJECT VACCINES INC
发明人
HAYNES, JOEL, R.;MACKLIN, MICHAEL, D.;PAYNE, LENDON, G.