| 发明名称 |
ANTISENSE MODULATION OF APAF-1 EXPRESSION |
| 摘要 |
<p>Antisense compounds, compositions and methods are provided for modulating the expression of Apaf-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targetd to nucleic acids encoding Apaf-1. Methods of using these compounds for modulation of Apaf-1 expression and for treatment of diseases associated with expression of Apaf-1 are provided.</p> |
| 申请公布号 |
WO0232921(A1) |
申请公布日期 |
2002.04.25 |
| 申请号 |
WO2001US32116 |
申请日期 |
2001.10.15 |
| 申请人 |
ISIS PHARMACEUTICALS, INC.;ZHANG, HONG;WATT, ANDREW, T. |
发明人 |
ZHANG, HONG;WATT, ANDREW, T. |
| 分类号 |
A61K38/00;C12N15/113;(IPC1-7):C07H21/04;C12Q1/68;A61K31/07;A01N43/04;C12N15/85 |
主分类号 |
A61K38/00 |
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