HYDROPHILIC LIGHT ABSORBING COMPOSITIONS FOR DETERMINATION OF PHYSIOLOGICAL FUNCTION IN CRITICALLY ILL PATIENTS
摘要
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume <i>in vivo</i>.
申请公布号
WO0232285(A2)
申请公布日期
2002.04.25
申请号
WO2001US31717
申请日期
2001.10.05
申请人
MALLINCKRODT INC.;ACHILEFU, SAMUEL;RAJAGOPALAN, RAGHAVAN;DORSHOW, RICHARD, B.;BUGAJ, JOSEPH, E.
发明人
ACHILEFU, SAMUEL;RAJAGOPALAN, RAGHAVAN;DORSHOW, RICHARD, B.;BUGAJ, JOSEPH, E.