NEW DERIVATIVES OF CYANO-ARYL (OR CYANOHETEROARYL)-CARBONYL-PIPERAZINYL-PYRIMIDINES, THEIR PREPARATION AND APPLICATION AS MEDICATION

摘要

The invention relates to new derivatives of cyano-aryl (or cyanoheteroaryl)-carbonyl-piperazinyl-pyrimidines (I), wherein R1 represents an OR3 radical, wherein R3 represents a radical deriving from a saturated hydrocarbon with a linear or branched chain of 1 to 4 carbon atoms and R2 represents a phenyl radical substituted at least by a cyano radical (-CN), or a radical of a 5 or 6-membered heteroaromatic ring substituted by at least one cyano radical (-CN). The physiologically acceptable salts of said derivatives can be used in human and/or veterinary therapeutic applications as sedatives, anticonvulsivants, hypnotics and general anesthetics.