发明名称 |
CHEMICAL COMPOUNDS |
摘要 |
Formula (1) wherein R represents a halogen atom or a C1-4 alkyl group; R1 represents a C1-4 alkyl group; R2 represents hydrogen or a C1-4 alkyl group; R3 represents hydrogen, or a C1-4 alkyl group; R4 represents a trifluoromety l group; R5 represents hydrogen, a C1-4 alkyl group or C(0)R6; R6 represents C 1- 4 alkyl, C3-7 cycloalkyl, NH(C1-4 alkyl) or N(C1-4alkyl)2; m is zero or an integer from 1 to 3; n is an integer from1 to 3 and pharmaceutically acceptable salts and solvates thereof; to processes for their preparation an d their use in the treatment of conditions mediated bytachykinins.
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申请公布号 |
CA2425876(A1) |
申请公布日期 |
2002.04.25 |
申请号 |
CA20012425876 |
申请日期 |
2001.10.12 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
ALVARO, GIUSEPPE;DI FABIO, ROMANO;TRANQUILLINI, MARIA ELVIRA;TAMPIERI, MARSIA;MARAGNI, PAOLO |
分类号 |
A61K31/445;A61K31/496;A61P25/00;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P25/36;C07D211/58;(IPC1-7):C07D211/58 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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