| 发明名称 |
Human PEM as a target for birth contol and treatment of Alzheimer's disease |
| 摘要 |
The invention relates to the human PEM polypeptide that plays an important role for the maturation of sperm and for Alzheimer's disease, and the nucleic acid that codes for them. The invention comprises the use of PEM as a target in male birth control and for the treatment and diagnosis of male infertility and Alzheimer's disease. The invention also includes a selection process for PEM antagonists as well as the production of binding molecules, which specifically detect PEM. In addition, genes that are regulated by the PEM gene are part of this invention.
|
| 申请公布号 |
US2002048764(A1) |
申请公布日期 |
2002.04.25 |
| 申请号 |
US20010867753 |
申请日期 |
2001.05.31 |
| 申请人 |
WEISS BERTRAM;GESERICK CHRISTOPH;HAENDLER BERNARD |
发明人 |
WEISS BERTRAM;GESERICK CHRISTOPH;HAENDLER BERNARD |
| 分类号 |
G01N33/50;A61K31/7088;A61K35/76;A61K38/00;A61K45/00;A61K48/00;A61P15/08;A61P15/16;A61P25/28;C07K14/47;C12N5/10;C12N5/22;C12N15/09;C12N15/12;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;(IPC1-7):C12Q1/68;C07H21/04;C12N5/08 |
主分类号 |
G01N33/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
