| 发明名称 |
Immunoregulator from the family designated 'leukocyte immunoglobulin-like receptors' (LIR) |
| 摘要 |
<p>A family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridizes to defined nucleotide sequences, processes for producing polypeptides of the LIR family, and specific antibodies directed against LIR polypeptides. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.</p> |
| 申请公布号 |
EP1199362(A2) |
申请公布日期 |
2002.04.24 |
| 申请号 |
EP20010130678 |
申请日期 |
2000.05.12 |
| 申请人 |
IMMUNEX CORPORATION |
发明人 |
COSMAN, DAVID, J.;ANDERSON, DIRK, M.;BORGES, LUIS |
| 分类号 |
C12N15/09;A61K38/00;A61K38/16;A61P37/02;A61P37/04;A61P37/06;C07K14/705;C07K14/735;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02;(IPC1-7):C12N15/12;C12N15/62;C07K19/00 |
主分类号 |
C12N15/09 |
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