发明名称 |
TC OR RE RADIOLABELLED SOMATOSTATIN ANALOGS |
摘要 |
<p>Technetium or rhenium radionuclide labelled chelate-hexapeptide complexes are useful for the selective detection or treatment of tumors with somatostatin receptors. In particular, compounds of formula: <IMAGE> (wherein R, R1, R3 and A are as defined herein) incorporating an N3S2 chelate may be labelled with a radionuclide. The resulting complexes are useful as radioimaging agents or as radiopharmaceuticals for the treatment of certain tumors.</p> |
申请公布号 |
EP0785951(B1) |
申请公布日期 |
2002.04.24 |
申请号 |
EP19950933284 |
申请日期 |
1995.10.11 |
申请人 |
MERCK FROSST CANADA & CO. |
发明人 |
FLANAGAN, RICHARD J.;DUFOUR, JEAN-MARC;HOGAN , KEITH T. |
分类号 |
A61K51/00;A61K38/00;A61K51/08;A61P35/00;C07K1/13;C07K14/655;(IPC1-7):C07K14/655 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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