INTIMATE MIXTURE OF CALCIUM AND PHOSPHATE SOURCES AS PRECURSOR TO HYDROXYAPATITE

摘要

Novel compositions are provided for the production of hydroxyapatite, where a dry mixture is provided which combines a calcium source and an acidic phosphate source, particularly monocalcium phosphate monohydrate or orthophosphoric acid crys- tals. These two are combined, optionally with other ingredients, with mechanical mixing, resulting in partial reaction or intimate combination to produce a product which requires less water for formation of a desired viscosity, has enhanced mechanical pro- perties and is physiologically acceptable.