摘要 |
medicine, organic chemistry, pharmacy. SUBSTANCE: invention proposes compounds of the formula (I): , i. e. (6R, 12aR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)- pyrazino[2',1':6,1]pyrido[3,4-b]indol-1,4-dione and (3S,6R,12aR)-2,3,6,7,12,12a-hexahydro-2,3-dimethyl-6-(3,4-methylenedioxyphenyl)-pyrazino[2', 1': 6,1] pyrido[3,4-b]indol-1,4- dione and physiologically acceptable salts and solvates used for treatment of patients with impotency. Invention proposes also method of treatment and prophylaxis of erectile dysfunction with indicated compounds and pharmaceutical compositions based on thereof. Invention proposes the method of preparing pharmaceutical compositions. EFFECT: enhanced activity of compounds proposed. 13 cl, 1 tbl, 3 ex
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