The present invention relates to synthetic gag and gagpol genes optimized for high level expression via codon optimization and the uses thereof for the efficient generation of vector particles. The invention further relates to the generation of packaging cells and vaccines based on the synthetic gag and gagpol genes.
申请公布号
WO0188141(A3)
申请公布日期
2002.04.18
申请号
WO2001EP05744
申请日期
2001.05.18
申请人
GENEART GMBH;WAGNER, RALF;GRAF, MARKUS;DEML, LUDWIG;BIELER, KURT
发明人
WAGNER, RALF;GRAF, MARKUS;DEML, LUDWIG;BIELER, KURT