发明名称 |
Method of treating colonic adenomas |
摘要 |
This invention is directed to a method of retarding or preventing the transformation of a colonic adenoma to a colonic adenocarcinoma comprising the administration to a patient with FAP or a patient with one or more of said adenomas a non-toxic therapeutically effective amount of NSAID, said amount effective to inhibit the PGHS-2 in said adenoma. The preferred method comprises the administration of a specific PGHS-2 inhibiting agent as defined herein.
|
申请公布号 |
US2002045605(A1) |
申请公布日期 |
2002.04.18 |
申请号 |
US20010976127 |
申请日期 |
2001.10.12 |
申请人 |
MERCK & CO. |
发明人 |
KARGMAN STACIA;EVANS JILLY;SIMON THOMAS J. |
分类号 |
A61K31/00;A61K31/12;A61K31/18;A61K31/19;A61K31/192;A61K31/195;A61K31/196;A61K31/34;A61K31/341;A61K31/365;A61K31/40;A61K31/405;A61K31/407;A61K31/54;A61K31/5415;(IPC1-7):A61K31/60;A61K31/404 |
主分类号 |
A61K31/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|