发明名称 |
Method of inhibiting angiogenesis and tumor growth and preventing tumor growth and metastases |
摘要 |
The invention is directed to a method for inhibiting angiogenesis and thus treating inflammatory diseases (e.g., rheumatoid arthritis, diabetic retinopathy, psoriasis, and macular degeneration), inhibiting and preventing tumor growth and preventing metastases in a mammal comprising administering to the mammal an effective amount of a monoclonal antibody which is an antagonist of the integrins, GPIIb/IIIa (alphaIIbbeta3) and alphavbeta3.
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申请公布号 |
US2002044936(A1) |
申请公布日期 |
2002.04.18 |
申请号 |
US20010855886 |
申请日期 |
2001.05.15 |
申请人 |
MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY, CENTOCOR INC. |
发明人 |
COLLER BARRY;JORDAN ROBERT;VARNER JUDITH |
分类号 |
C12P21/08;A61K38/00;A61K39/395;A61P9/00;A61P17/06;A61P27/02;A61P29/00;A61P35/00;A61P35/04;C07K16/18;C07K16/28;C12R1/91;(IPC1-7):A61K39/395 |
主分类号 |
C12P21/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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