| 发明名称 |
EFFICIENT METHOD OF SYNTHESIZING COMBRETASTATIN A-4 PRODRUGS |
| 摘要 |
Methods of synthesizing a phosphate ester of combretastatin A-4 and <i>trans</i>-isomers thereof in which combretastatin A-4 is reacted with dibenzylphosphite in the presence of carbon tetrabromide, or with 2,2,2-trichloroethyl phosphorodichloridate, to form a phosphate ester of combretastatin A-4 with protecting groups thereon. |
| 申请公布号 |
WO0206279(A3) |
申请公布日期 |
2002.04.18 |
| 申请号 |
WO2001US22403 |
申请日期 |
2001.07.17 |
| 申请人 |
OXIGENE, INC. |
发明人 |
SEYEDI, FAYE;GALE, JONATHAN;HAIDER, REEM;HOARE, JOHN |
| 分类号 |
C07F9/12 |
主分类号 |
C07F9/12 |
| 代理机构 |
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