发明名称 |
ARTIFICIAL TRANSCRIPTIONAL FACTORS AND METHODS OF USE |
摘要 |
An artificial transcription factors (ATF) is provided having a non-peptidic-DNA binding domain, flexible linker and a short synthetic effector domain. The ATFs are highly potent transcriptional modulators <i>in vitro</i> and <i>in vivo</i>. Methods for targeted manipulation of gene expression and the development of new class of pharmaceuticals are also provided. |
申请公布号 |
WO0231166(A2) |
申请公布日期 |
2002.04.18 |
申请号 |
WO2001US32000 |
申请日期 |
2001.10.15 |
申请人 |
CROSSLINK GENETICS CORPORATION |
发明人 |
STANOJEVIC, DUSAN |
分类号 |
C12N15/09;C07K14/00;C12N15/113;C12N15/63;C12Q1/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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