摘要 |
<p>A bioassay reagent is provided consisting of a xenogeneic antibody containing plasma. Specifically, the bioassay reagent disclosed contains plasma from a first animal species and antibodies derived from at least one second different animal species that recognize antigens indigenous to the first animal species. More specifically, a bioassay for assessing the efficacy of therapeutics intended to treat patients having autoimmune diseases, specifically, hemophiliacs having anti-blood factor antibodies (inhibitory factors) present in their blood. Also provided are associated methods for making and using the bioassay reagents disclosed.</p> |