| 发明名称 |
PYRIMIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ATHEROSCLEROSIS |
| 摘要 |
Compounds of formula (I) are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating athereosclerosis.
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| 申请公布号 |
CA2459746(A1) |
申请公布日期 |
2002.04.18 |
| 申请号 |
CA20012459746 |
申请日期 |
2001.10.05 |
| 申请人 |
SMITHKLINE BEECHAM PLC |
发明人 |
PINTO, IVAN LEO;SMITH, STEPHEN ALLEN;LEACH, COLIN ANDREW;ELLIOTT, RICHARD LEONARD;HICKEY, DEIRDE MARY BERNADETTE;IFE, ROBERT JOHN |
| 分类号 |
A61K31/513;A61K31/517;A61K31/519;A61K31/5377;A61P3/10;A61P9/00;A61P9/10;A61P17/06;A61P19/02;A61P25/28;A61P29/00;A61P31/04;A61P43/00;C07D239/36;C07D239/70;C07D239/90;C07D239/91;C07D401/12;C07D403/12;C07D405/14;C07D409/12;C07D409/14;C07D471/04;C07D487/04;C07D495/04;(IPC1-7):C07D239/91;A61K31/505 |
主分类号 |
A61K31/513 |
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