发明名称 INTRACELLULAR DELIVERY OF BIOLOGICAL EFFECTORS BY NOVEL TRANSPORTER PEPTIDE SEQUENCES
摘要 The invention relates to a sequence of amino acids with the capacity to facilitate transport of an effector across a biological membrane. More specifically, the present invention relates to novel peptide transporter tha t specifically target certain cell types for the intracellular delivery of dru gs and therapeutic agents, comprising at least one amino acid sequence selected from the group consisting of: a) (XmRXoRXn); b) (XmRRRXn); c) (XmRRXRXn); an d d) (XmRXRRXn), wherein X is a non-basic amino acid; m is an integer from zer o to fourteen; n is an integer, independent of m, between zero and fourteen; o is an integer, independent of m and n, between zero and five; and wherein sa id transporter peptide is capable of translocating across a biological membrane .
申请公布号 CA2425610(A1) 申请公布日期 2002.04.18
申请号 CA20012425610 申请日期 2001.10.15
申请人 UNIVERSITY OF LAUSANNE 发明人 BONNY, CHRISTOPHE
分类号 G01N33/53;A61K31/7088;A61K38/00;A61K38/06;A61K45/00;A61K47/48;A61K48/00;A61P3/10;A61P5/48;A61P9/00;A61P9/04;A61P11/00;A61P25/00;A61P25/28;A61P31/12;A61P35/00;C07K1/04;C07K5/10;C07K5/103;C07K5/107;C07K5/11;C07K5/113;C07K7/06;C07K7/08;C07K19/00;C12Q1/70;G01N33/566;(IPC1-7):C07K5/068;A61K38/05;A61K38/07;A61K38/08;C07K5/09;A61K38/10;C07K14/47 主分类号 G01N33/53
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