发明名称 |
BENZIMIDAZOLE COMPOUNDS |
摘要 |
<p>A benzimidazole compound or a salt thereof which has an inhibitory action of forming of macrophages and is useful as an active ingredient of an orally available medicament for preventive and/or therapeutic treatment of arteriosclerosis, which is represented by the formula (I): <CHEM> wherein, R<1> represents one or more functional groups on the benzene ring selected from the group consisting of hydrogen atom, a halogen atom, a lower alkyl group and a lower alkoxy group; R<2> represents hydrogen atom, an alkyl group or an acyl group; L represents a C4-C8 alkylene group or an ethyleneoxy linking group represented as (CH2CH2O)nCH2CH2 wherein n represents 1 or 2; X represents O or NH; Y represents S or a single bond; and Q represents a 5- or 6-membered heterocyclic group which may have a functional group on the ring.</p> |
申请公布号 |
EP1197493(A1) |
申请公布日期 |
2002.04.17 |
申请号 |
EP20000944320 |
申请日期 |
2000.07.07 |
申请人 |
FUJI PHOTO FILM CO., LTD. |
发明人 |
AOKI, KOZO;AIKAWA, KAZUHIRO;KAWAKAMI, MASAYUKI;YAN, YONGZHE |
分类号 |
A61P3/06;A61P9/10;C07D235/28;C07D401/12;C07D403/12;C07D413/12;C07D417/12;(IPC1-7):C07D403/12;A61K31/496;A61K31/418;A61K31/443;A61K31/428;A61K31/423;A61K31/419 |
主分类号 |
A61P3/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|