BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME

摘要

A benzimidazole compound or a salt thereof which has an inhibitory action of forming of macrophages and is useful as an active ingredient of a medicament for preventive and/or therapeutic treatment of arteriosclerosis, which is represented by the formula (I): <CHEM> wherein R<1> represents hydrogen atom, a halogen atom, a lower alkyl group, or a lower alkoxy group; R<2> represents hydrogen atom, an alkyl group, or an acyl group; R<3> represents a functional group on the ring; A represents O or CH2, or CH that forms a double bond with an adjacent carbon atom; L represents a C4-C8 alkylene group or an ethyleneoxy linking group represented by (CH2CH2O)nCH2CH2 wherein n represents 1 or 2; X represents O, S or methylene group; and m represents 0 or 1.