发明名称 Synthetic peptides and their use in cosmetic or dermopharmaceutical compositions
摘要 The invention concerns the use of peptides of general formula R1-L-Tyr-L-Arg-R2 in which R1=H or a R3-C=0 with R3=a C1 to C20 alkyl chain, linear or branched, saturated or unsaturate, hydroxylated or not, or with R3=an aryl, aryl-alkyl or alkyloxy or aryloxy or arylalkyloxy group, and in which R2=OH or a O-R4 group with R4=a C1 to C20 alkyl chain, or R2=a NH2, NHX or NXX group with X=a C1 to C4 alkyl chain. The peptides have a soothing effect on the skin, including by topical application, and attenuates the effects of benign skin sores (after shave irritation, sunstroke, frostbite, chaps, depilation). They are used in acceptable cosmetic excipients and in effective in vivo concentrations.
申请公布号 US6372717(B1) 申请公布日期 2002.04.16
申请号 US19990242687 申请日期 1999.02.23
申请人 SEDERMA S.A. 发明人 GREFF DANIEL
分类号 A61K8/64;A61K38/00;A61K38/05;A61Q19/00;C07K5/065;(IPC1-7):A61K38/00;C07K7/00;G01N33/00 主分类号 A61K8/64
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