发明名称 7-carboxy-flavone derivatives, preparation method and therapeutic use
摘要 The invention concerns novel flavone and isoflavone derivatives of formulae (Ia) and (Ib) wherein: X represents a group of formula -COOR, or -PO(OR)<SUB>2</SUB>; R represents a hydrogen atom or an alkaline or alkaline-earth metal, or a lower alkyl group; R<SUB>1 </SUB>represents a hydroxy group, a lower alkoxy group or an acyloxy group; R<SUB>2 </SUB>and R<SUB>3</SUB>, identical or different, represent a hydrogen or halogen atom, or a trifluoromethyl group, a trichloromethyl group, a hydroxy group, an alkoxy group or an acyloxy group comprising 1 to 5 carbon atoms, or R<SUB>2 </SUB>and R<SUB>3 </SUB>can combine to form an alkylene dioxy group. The invention is useful for rheumatic diseases.
申请公布号 AU9395601(A) 申请公布日期 2002.04.15
申请号 AU20010093956 申请日期 2001.10.05
申请人 NEGMA-LERADS 发明人 JEAN-PIERRE GESSON;NADIA FONTENEAU;MARTINE MONDON;SUZY CHARBIT;HERVE FICHEUX;FRANCOIS SCHUTZE
分类号 A61K31/352;A61P19/02;A61P29/00;A61P43/00;B01J31/24;C07D311/30;C07D311/36;C07F9/655 主分类号 A61K31/352
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