发明名称 |
Vector system |
摘要 |
The present invention relates to retroviral vector genomes and to vector systems comprising such genomes. In particular the present invention relates to a retroviral vector genome comprising two or more NOIs operably linked by one or more Internal Ribosome Entry Site(s); a lentiviral vector genome comprising two or more NOIs suitable for treating a neurodegenerative disorder; and a lentiviral vector genome which encodes tyrosine hydroxylase, GTP-cyclohydrolase I and optionally Aromatic Amino Acid Dopa Decarboxylase. |
申请公布号 |
AU9209301(A) |
申请公布日期 |
2002.04.15 |
申请号 |
AU20010092093 |
申请日期 |
2001.10.05 |
申请人 |
OXFORD BIOMEDICA (UK) LIMITED |
发明人 |
ALAN JOHN KINGSMAN;NICHOLAS D. MAZARAKIS;ENCA MARTIN-RENDON;MIMOUN AZZOUZ;JONATHAN ROHLL |
分类号 |
C12N15/09;A61K35/76;A61K48/00;A61P25/16;A61P25/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/00;C12N9/02;C12N15/867 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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