发明名称 |
Compositions and methods for designing and using compositions which inhibit activated helper t cells |
摘要 |
Compositions containing compounds and methods for identifying and designing compounds with a basic pharmacophore which disrupts a primary activation signal in Helper T cells and induces death or anergy of activated cells are provided. Also provided are methods of using these compositions to inhibit CD4 activity and undesired immune responses which result therefrom. |
申请公布号 |
AU9496801(A) |
申请公布日期 |
2002.04.15 |
申请号 |
AU20010094968 |
申请日期 |
2001.10.02 |
申请人 |
PHILADELPHIA, HEALTH AND EDUCATION CORPORATION |
发明人 |
BRADFORD A. JAMESON;ANNA TRETIAKOVA |
分类号 |
A61K31/195 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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