发明名称 DERIVES DE 7-CARBOXY-FLAVONES, PORCEDE POUR LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
摘要 The invention concerns novel flavone and isoflavone derivatives of formulae (Ia) and (Ib) wherein: X represents a group of formula -COOR, or -PO(OR)2; R represents a hydrogen atom or an alkaline or alkaline-earth metal, or a lower alkyl group; R1 represents a hydroxy group, a lower alkoxy group or an acyloxy group; R2 and R3, identical or different, represent a hydrogen or halogen atom, or a trifluoromethyl group, a trichloromethyl group, a hydroxy group, an alkoxy group or an acyloxy group comprising 1 to 5 carbon atoms, or R2 and R3 can combine to form an alkylene dioxy group. The invention is useful for treating rheumatic diseases.
申请公布号 FR2815033(A1) 申请公布日期 2002.04.12
申请号 FR20000012846 申请日期 2000.10.06
申请人 LABORATOIRES NEGMA 发明人 CESSON JEAN PIERRE;FONTENEAU NADIA;MONDON MARTINE;CHARBIT SUZY;FICHEUX HERVE;SCHUTZE FRANCOIS
分类号 A61K31/352;A61P19/02;A61P29/00;A61P43/00;B01J31/24;C07D311/30;C07D311/36;C07F9/655 主分类号 A61K31/352
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