摘要 |
The present invention provides methods and compositions for scre ening, diagnosis and prognosis of BAD, for monitoring the effectiveness of BAD treatment, and for drug development. BAD-Associated Features (DFs), detectable by two-dimensional electrophoresis of cerebrospinal fluid, serum or plasma are described. The invention further provids BAD-Associated Protein Isoforms (DPIs) detectable in cerebrospinal fluid, serum or plasma, preparations comprising isolated DPIs, antibodies immunospecific for DPIs, and kits comprising the aforesaid. |
申请人 |
OXFORD GLYCOSCIENCES (UK) LIMITED;HERATH, HERATH, MUDIYANSELAGE, ATHULA, CHANDRASIRI;PAREKH, RAJESH, BHIKHU;ROHLFF, CHRISTIAN |
发明人 |
HERATH, HERATH, MUDIYANSELAGE, ATHULA, CHANDRASIRI;PAREKH, RAJESH, BHIKHU;ROHLFF, CHRISTIAN |