USE OF MEK1 INHIBITORS AS PROTECTIVE AGENTS AGAINST DAMAGE DUE TO ISCHEMIA
摘要
The invention relates to the use of MEK1 inhibitors to reduce tissue damage resulting from ischemia and/or reperfusion, particularly brain damage associated with ischemia resulting from stroke. The invention also relates to the use of MEK1 inhibitors to treat hypoxia or glutamate toxicity. Pharmaceutical compositions, kits and perfusion fluids including MEK1 inhibitors are also provided.
申请公布号
WO0228388(A2)
申请公布日期
2002.04.11
申请号
WO2001US42480
申请日期
2001.10.05
申请人
THE GENERAL HOSPITAL CORPORATION;ALESSANDRINI, ALESSANDRO;BONVENTRE, JOSEPH;MOSKOWITZ, MICHAEL;NAMURA, SHOBU
