PROMOTERS FOR THE PROLIFERATION AND DIFFERENTIATION OF STEM CELLS AND/OR NEURON PRECURSOR CELLS

摘要

Promoters for the proliferation and differentiation of stem cells and/or neuron precursor cells, containing compounds of the following general formula, salts thereof, or prodrugs of both: wherein R<1> and R<2> are each H, a hydrocarbon group, a heterocyclic group, or R<1> and R<2> together with the carbon atom adjacent thereto may form a ring; R<3> is H, a hydrocarbon group, or a heterocyclic group; W is a group of the general formula (1), (2) or (3): (1) (2) (3) (wherein A is an optionally substituted benzene ring; B is an optionally substituted 5- to 7-membered nitrogenous hetero- cycle; R<4> is acyl which is substituted with an aromatic group and additionally bears an optionally substituted aliphatic hydrocarbon group or an aromatic group; R<5> is H, C1-6 alkyl, or acyl; R<4C> is an aromatic group, an aliphatic hydrocarbon group, or acyl; and X is O or S); Y is O, S, or NH; and C is an optionally substituted benzene ring.