| 摘要 |
This invention relates to 3/thioxo/[1,2,4]-oxadiazinan-5-one derivatives of formula: (I), wherein R is alkyl, alkenyl, or alkynyl; R1 and R2 are each independently hydrogen, alkyl, or aryl; and Ar is phenyl, indanyl, benzhydryl, or phenyl, substituted with one or more groups selected from the group consisting of halogen, alkyl, perfluoroalkyl, lower alkoxy, perfluoroalkoxy, dialkylamino, and aroyloxy; that elevate HDL cholesterol concentration, and which may be useful for the treatment of atherosclerotic conditions such as coronary heart disease.
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