发明名称 Amino acid derivatives
摘要 There is provided amino acid derivatives of formula I, wherein p, q, R1, R2, R3, R4, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as hirombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
申请公布号 US2002042396(A1) 申请公布日期 2002.04.11
申请号 US20010995564 申请日期 2001.11.29
申请人 ASTRA AB 发明人 GUSTAFSSON DAVID;NYSTROM JAN-ERIK
分类号 C07K5/06;A61K31/395;A61K31/397;A61K31/40;A61K31/4025;A61K31/443;A61K31/445;A61K38/05;A61K38/55;A61P7/02;C07D205/04;C07D207/16;C07D211/60;C07D405/06;(IPC1-7):A61K31/695;C07F7/02;C0747/14;A61K31/454;A61K31/401 主分类号 C07K5/06
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